Taking advantage of the great improvements in large-scale proteomic analysis of complex samples, we use state-of-the-art mass spectrometry techniques to study the molecular mechanisms of the inflammatory and immune responses in specific cellular systems, such as endothelial cells and different types of immune cells.
Major research axis:
- Proteomic analysis of the inflammatory response of endothelial cells
- Functional mechanisms of interleukin-33, a cytokine playing a major role in innate immunity and allergy
- Fine molecular characterization of the T Cell Receptor (TCR) pathway of T lymphocytes
- In-depth proteomic analysis of regulatory T cells (Tregs)
Scientific coordinator of the project: Anne Gonzalez de Peredo