Our aim is to understand how cancer driver mutations affect the assembly and function of ribosomes and can trigger malignancy phenomena.
To address this question, the candidate will mainly use structural biology approaches (cryo-EM and analysis of isolated particles, proteomics) which will then be integrated with other methodologies (NGS, RiboMethSeq) carried out by other members of the research consortium.
- To perform research work that fulfils the requirements of the project objective
- To interpret and present research data and results
- To ensure the validity and reliability of data at all times
- To carry out scientific and methodological watch relative to the project
- To present findings to colleagues and at conferences.
- To write up the finding for submission to refereed journals
- To take responsibility for organising resources and effective decision making in support of research.
- Training (Ph.D.) in structural biochemistry required
- Experience in cryo-EM and single particle analysis and/or proteomics is recommended.
- Knowledge about ribosomal assembly / functioning is a plus.
- The candidate will be motivated to take up scientific challenges.
- The candidate will have a strong capacity to work in a team, within a network of partners.
- The candidate will demonstrate good writing and communication skills in English, and an ability to publish and promote research work.
How to apply:
Detail on CNRS website